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Perbedaan Jumlah Trombosit Platelet Rich Plasma Yang Menggunakan Tabung Natrium Sitrat Dan Tabung ACD-A Sheila Clarissa; Jusak Nugraha; Triagung Ruddy
JURNAL WIDYA MEDIKA Vol 5, No 1 (2019)
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Background: PRP is a relatively new field and there is still minor researches that are usage. However, PRP can be applied to a lot of various fields. This study willmake a comparison between tubes that have sodium citrate anticoagulant and tubes that have ACD-A anticoagulants, to be able to find out which of the two are able to produce a higher number of PRPs. Objective: To obtain the anticoagulants that produce more platelet countsand to know the difference in the platelet counts in PRPs found in tubes that have sodium citrate anticoagulants and tubes that have ACD-A anticoagulants. Method: This study was an experimental laboratorium research with an equivalent control group design. Data is normally distributed, so that the parametic statistical analysis test uses Paired T-Test. Results: From 32 respondents, there was an increase in both anticoagulant tubes, where the average increase in platelet counts in PRP using sodium citrate tubes was 337593.75 / μl and the standard deviation was 158795.437 whereas, the average increase in platelet counts in PRP using ACD-A tubes was 909062.50 / μL and the standard deviation is. 284336.005. The difference in platelet counts in PRP using sodium citrate tubes and ACD-A tubes was stated to be significant because the result of the Paired T-Test analysis showed Sig (2-Tailed) = 0,000 (p

Exertional Heatstroke, Asesmen Cepat Dan Penatalaksanaan Tepat: Laporan Kasus . Melinda; Filipus Michael Yofrido; Philia Setiawan
JURNAL WIDYA MEDIKA Vol 5, No 1 (2019)
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Heatstroke is the most severe heat illness which homeostatic thermoregulatory mechanism is failed, characterized by an elevation of the core body temperature above 40 oC, central nervous system dysfunction, and possible multi-organ failure. Heatstroke is the third leading cause of death among athletes. Exertional heatstroke (EHS) is exercise-induced; usually affects young healthy people during strenuous physical activity and have not acclimatized to environmental heat stress. Frequently encountered complications include encephalopathy, acute respiratory distress syndrome, myocardial injury, acute kidney injury, hypoglycemia, intestinal ishemia or infarction, pancreatic injury, rhabdomyolysis, disseminated intravascular coagulation (DIC), hypocalcemia, lactic acidosis, and hepatic failure. Immediate cooling is the cornerstone of treatment which evaporative cooling is preferred. Aspiration and seizure are common; airway management, oxygenation, and ventilation have to be adequately maintained. Crystalloid-fluid resuscitation is essential, averaging 1200 mL in first 4 hours. Systemic complications of heatstroke should be well-managed to prevent worse outcome. A case of 32-years-old man with no significant medical history was brought to emergency department after collapsing while running into the 20-kilometres marathon. He was unresponsive (GCS E1V2M1), had serial generalized seizure and hematemesis-melena. On primary survey, the patient was shocked (BP 67/24 mmHg, HR 165 bpm, cold extremity), tachypnea (41/min), hyperthermia (40.5oC rectally), SpO2 95% on simple mask 10 L/min. His laboratory results showed full-blown complications of heatstroke. Immediate rehydration therapy using saline solution and colloid solution intravenously was started, followed with blood or blood component transfusion. Tracheal intubation and mechanical ventilation were performed. During the intensive treatment, he became fully conscious and was extubated on hospital day 7. He was hemodynamically stable without any support, but developed multi-organ failure. Unfortunately, on twentieth day, he was cardiac arrest during hemodialysis and died four days later.

Asosiasi Antara Situasi Emosi, Kepatuhan Pada Oral Anti Diabetes, dan Hemoglobin Terglikasi Pada Penyandang Diabetes Mellitus Tipe 2 Inge Wattimena; Galuh Nawang Prawesti
JURNAL WIDYA MEDIKA Vol 5, No 1 (2019)
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

The problem of diabetes, which is predicted to increase in number of people suffering from diabetes in the upcoming years, needs to be examined from a bio-psycho-social perspective. This chronic illness which is difficult to be cured, affects the emotional situation and also the adherence to oral anti-diabetes (OAD). The objective of this study is to examine the relationship between bio-physiology of the body (measured by the glycated hemoglobin level of HbA1c) and the emotional situation and adherence to OAD. Observational research with a cross-sectional approach was carried out on 76 type 2 diabetics who were treated at the Gotong Royong Hospital (RSGR) Surabaya. Research data was taken through a valid and reliable questionnaire about emotional situation and adherence to OAD. The glycated hemoglobine was measured in the RSGR laboratory. Inferential analysis was tested using Spearman correlation test. The results showed a significant negative correlation power between the emotional situation and the level of HbA1c (r = -0.256, p = 0.026), as well as between the level of adherence to OAD and the level of HbA1c (r = -0.402, p = 0.000). Those outcomes indicated that the more positive the emotional situation, as well as the higher the level of adherence to OAD, the better health outcome of the diabetic patient. These results enrich the educational material in health promotion. Enhancing the positive emotional situation and the level of adherence to OAD will decrease the morbidity and mortality rates due to diabetes, and optimize the welfare of the patient.

The Association Between Risk Factors And Ultrasound-Based Grades Of Non-Alcoholic Fatty Liver Disease In Type-2 Diabetes Patients FX Himawan Haryanto Jong; Prettysun Ang Mellow
JURNAL WIDYA MEDIKA Vol 5, No 1 (2019)
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Background: Non-alcoholic fatty liver disease (NAFLD) has become more common as the cause of cirrhosis and liver cancer. The liver disease is highly prevalent in people with type-2 diabetes. Indonesia is not spared from the global epidemic of type-2 diabetes. The ultrasound examination is clinically easy-to-use, economical and non-invasive as a tool to detect NAFLD, compared to the gold standard, liver biopsy. To date, there has been no study in Indonesia to link risk factors and ultrasound-based severity grading of NAFLD. Aim: To understand the association between risk factors and ultrasound-based grades of NAFLD in patients with type-2 diabetes. Method: The present study was an observational study with a cross-sectional design (May-October 2018) that involved 82 type-2 diabetes outpatients of the internal medicine clinic in the Gotong Royong Hospital (Surabaya, Indonesia). The risk factors assessed were gender, age, diabetes duration, obesity (anthropometric measurement: body mass index/ BMI, waist circumference and waist-to-hip ratio), glycemic control (hemoglobin A1c/ HbA1c level) and dyslipidemia (lipid profile: total cholesterol, low-density lipoprotein/ LDL, high-density lipoprotein/ HDL and triglyceride). The ultrasound-based grades of NAFLD consisted of grade 0 (no NAFLD), grade 1 (increased liver echogenicity with normal images of intrahepatic vessel lines and diaphragm), grade 2 (blurred image of intrahepatic vessel lines) and grade 3 (blurred images of intrahepatic vessel lines and diaphragm). Statistical p-value was significant at ≤ 0.05. Results: Seventy-eight subjects (95,1%) had NAFLD. The ultrasound-based NAFLD grades were significantly different across age groups (Kruskal-Wallis) but the Spearman’s rank correlation test result was not significant. Body mass index and total cholesterol were positively correlated (r = 0.390 and 0.237, respectively) with the NAFLD grades. Conclusion: Higher BMI and total cholesterol are associated with increased ultrasound-based NAFLD grades.

Evaluasi Status Fungsional Pasien Stroke Iskemik Di Ruang Rawat Inap Saraf RSUD Dr. Soetomo Menggunakan Instrumen Functional Independence Measure (FIM) Inez Anabela Suprijadi Suprijadi; Florentina Sustini; I Putu Alit Pawana; Devi Ariani Sudibyo
JURNAL WIDYA MEDIKA Vol 5, No 1 (2019)
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Introduction: Stroke is a sudden and acute functional focal and global brain disorder that lasts more than 24 hours due to brain blood circulation disorders. Strokes can influence several aspects of life including ADL. Aim: To analyze the patients with ischemic stroke in Neurology Department of RSUD Dr. Soetomo by Functional Independence Measure (FIM) scale at the times of admission to hospital, discharge, and one month after follow-up. Methods: The design of study was cohort. Sample was 60 patients that suitable with the inclusion criteria and was selected by consecutive sampling. Patient’s age, sex, length of stay, nutritional intake, compliance of drugs intake, and the ability of physical activity were recorded. After that, motor assessment and daily activities skills were evaluated by FIM scale. Data was collected by interview and examination for 5 months. Data was analyzed by t-test. Results: A sum of 60 patients are studied. Most frequent genders are male (53,3%), age ranging from 60-69 years old (36,7%), length of stay mostly less than a week (88,3%), nutritional intake is mostly balanced (31,7%), most of the patients take their drugs regularly (66,7%), and most of the patients are only need supervision (45%). The FIM score at admission ranged between 54-71 (40%), at discharged ranged between 72-89 (46,7%), and after one month follow-up ranged between 72-89 (48,3%). There were significant change at p=0,001 between FIM Score at discharged and admission and also between FIM score after one month follow-up and discharged. Conclusion: All patients’ FIM scores were improved. There was a correlation between patient’s length of stay and FIM score at admission and also the ability of physical activity. Significant correlation was found between patient’s age and the ability of physical activity with the FIM score at discharge. Patient’s age, length of stay, and the ability of physical activity have significant correlation with The FIM score after one month follow-up.

Efek Injeksi Plasma Kaya Platelet Terhadap Tenosinovitis Tendon Tibialis Posterior: Sebuah Studi Kasus Henry Ricardo Handoyo; Andryan Hanafi Bakri; Andri Primadhi
JURNAL WIDYA MEDIKA Vol 5, No 1 (2019)
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Introduction: Posterior tibial tendon dysfunction is one of the most common, problems of the foot and ankle. Tenosynovitis of the posterior tibial tendon (PTT) is an often unrecognized form of PTT dysfunction. Case: A 54-year-old woman presented with left ankle pain that began while morning walk three days prior. She noted that the left ankle hurt with even light touch and the pain was unrelieved with sodium diclofenac. She denied any history of trauma. She was seen in the outpatient clinic for this condition. On examination, a three centimeter area of pain was found posterior to the medial malleolus and parallel to the PTT. She also had a stage I flat foot and mild soft tissue swelling around medial malleolus region on her radiograph examination. Ultrasound examination was done with the result of anechoic fluid visible in the peritendinous space around the PTT. The patient received diagnosis of PTT tenosynovitis, with the foot and ankle disability index (FADI) score was 58.7. Platelet rich plasma (PRP) injection was done twice with an interlude of two weeks. The pain subsided and the following FADI score was 84.6. Outcome: Patient showed improvement in her left ankle PTT tenosynovitis after two PRP injection. Conclusion: This case report highlights the efficacy of PRP as a modality in managing PTT tenosynovitis.

Pengaruh Ekstrak Etanolik Atau Ekstrak Dekok Ganoderma Lucidum (ß Glucan) Terhadap Hormon Testosteron, Sel Leidiq Testis Rattus Norvegicus Jantan. Bambang Wasito Tjipto
JURNAL WIDYA MEDIKA Vol 5, No 1 (2019)
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

The process of "aging" causes a decline in physical and mental strength. In general, more and more bodily organs are complained of by elderly people, and suffer from chrnic diseases. Older men experience various changes including a decrease in endocrine, cardiovascular, neurological, eye, skin, reproductive and so on. The Late Onset Hypogonadism (LOH) is a syndrome that decreases sexual, physical, and psychological abilities associated with a decrease in testosterone levels in the blood. In middle age, the age of 45-59 years begins to decrease body function, including decreased reproductive function and the function of sexuality, hormones such as testosterone. which is known as aging process. Testosterone is an anabolic hormone. Giving Ganoderma Lucidum in a preliminary study of normal one-year-old male Rattus norvegicus rats, water extract (dekok) and ethanol extract with different doses, 10 mg / kg, 20 mg / kg bw, and 30 mg kg / bb proved to increase total testosterone hormone serum significantly at a dose of 30 mg / kg bw, then researchers increase the dose to 50 mg / kg bw. Purpose of the study: Analyzing the effect of dekok extract or Ganoderma lucidum ethanolic extract on the hormone testosterone, testicular Leidiq cells that are undergoing the aging process. Results: Test profile of testosterone, after administration between controls, extract of dekok and male ethanol extract of 18 months old male Leydig Rattus norvegicus testis. In different tests on testosterone, there were significant differences between controls, dekok extract and ethanol extract. The results of testosterone levels in ethanol extract were higher. Conclusion: Dekok and Ganoderm lucidum ethanol extract can increase testosterone hormone

The Role Of Rose (Rapid Onsite Evaluation) On Spinal Lesion Surgery Decision . Sindrawati; Komang Agung; Carlos Binti; Anggita Dewi
JURNAL WIDYA MEDIKA Vol 5, No 1 (2019)
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Introduction: Exposure and instrumentation of the spine must be meticulous and thorough regardless the techniques and approach selected. Management of the whole surgery process should be decided based on the best available evidence whenever possible. ROSE (Rapid Onsite Evaluation) cytology wrap up the surgical decision. Case Description: Fifteen cases comprise of lytic lesions and/or single pathological fractures of the corpus vertebrae will be presented and discuss as to how the surgical techniques and approaches are assisted by ROSE. ROSE cytology was performed in the operating theater during the surgery. Samples were taken after exposure of the minimal lesion using (18–21) G trocar needle or under fluoroscopy guided. Direct smear, air dried fixation, and Diff Quik staining would take about 10 minutes. Pathologist evaluated the specimen and provided the result in about 20 minutes. The overall 30 minutes allowed surgeon to prepare the further steps. Results would be malignant or benign without pursuing further detail diagnostic. Benign results should be categorized as infection, suspicious of granulomatic tuberculosis, or normal host population cells. The cases outcome were 8 normal host population cells advanced for vertebroplasty to fill the porotic bone. Three spondylitis tuberculosis were debrided without unnecessary instrumentation, and four malignant processes were assured to have enough samples for immunohistochemistry evaluation afterward. All ROSE cytology was confirmed accordingly by the histopathology result afterward. Conclusion: ROSE is easy and offers accurate sampling from the lesion itself. It is quick, therefore during surgery surgeon could decide the best management for the patient.

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Contact Name
Vincentius Widya Iswara

Contact Email
vincentius@ukwms.ac.id

Phone
-

Journal Mail Official
jakobus@ukwms.ac.id

Editorial Address
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Location
Kota surabaya,

Jawa timur

INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Vincentius Widya Iswara

Contact Email vincentius@ukwms.ac.id

Phone -

Journal Mail Official jakobus@ukwms.ac.id

Editorial Address -

Location Kota surabaya, Jawa timur INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Vincentius Widya Iswara

Contact Email
vincentius@ukwms.ac.id

Phone
-

Journal Mail Official
jakobus@ukwms.ac.id

Editorial Address
-

Location
Kota surabaya,

Jawa timur

INDONESIA